ATROPINĂ SULFURICĂ 1 %
Solution for injection
100 ml Atropină sulfurică contain:
Active substance: atropine sulfate 1 g;
Excipients (hydrochloric acid 0.1 N, water for injection) up to 100 ml
Atropine is a parasympatholytic compound with strong antispastic, anti-secretory and mydriatic effects.
Horses, cattle, sheep, swine, goats, cats, dogs, fowls and pigeons
For reducing pain and peristalsis, in enterospasms, in intestinal invagination, acute enteritis, spasms and esophagus obstructions, in bronchial spasms, as respiratory stimulator in morphine intoxications, to prevent cardiac and respiratory syncope, in volatile narcotics anesthesia, to reduce bronchial secretions in other general anesthesia, as antidote in parasympathomimetic intoxications (arecoline, vasoperif, eserine, pylocarpine), as well as in organophosphorous intoxications (neguvon, clorophos, diazinon etc.). In the periodic ophtalmia of horse, it is used alternatively with some parasympathomimetics (e.g. pylocarpine).
Do not use in animals allergic to atropine
Agitation or rush may occur sometimes. In case of overdose, the following symptoms may appear: dry oral mucosa, mydriasis, agitation and tachycardia.
Method of administration
Inoculate the following doses by subcutaneous route:
- In horses, cattle: 3-5 ml (0.03-0.05 g). As antidote in parasympathomimetic intoxications, the recommended dose is 4-10 ml (in adult cattle), 3-8 ml (in horses) and in severe cases inoculate by intravenous route. Use 3-4 ml in bronchial spasms in adult cattle and 2-3 ml in horses.
- In sheep, swine, calves, foals, goats: 0.5-1 ml (0.005-0.01 g);
- In dogs, cats, fowls: 0.1-0.5 ml (0.001-0.005 g).
During strokes in regular ophthalmic disease (early stage), apply as instillations in the conjunctival sack, 3-4 drops and alternate with myotics (pylocarpine).
- In pigeons: as antidote in intoxications with organophosphorous pesticides and carbamates (intoxication with field-treated beans) or in intoxications with diazinon. Dilute ATROPINĂ SULFURICĂ 1% 10 times with distilled water and administer 3-5 drops at the bottom of the mouth and resume after 3-4 hours.
Administer with caution in case of renal and/or hepatic failure, high blood pressure, chronic bronchitis, due to the increase of the tracheal secretion viscosity.
Administer atropine slowly, by subcutaneous or intravenous route depending on the disease. Administer only under medical supervision.
Caution when administering with other alkaloids (they can enhance or block the effect of atropine). Phenothiazines (with the same antimuscarinic effect as atropine) may cause synergetic effects with atropine.
Vials of 20 ml.