Live freeze-dried vaccine against Newcastle Disease, prepared with Cl-90 strain
Newcastle disease virus, La Sota Cl-90 lentogenic strain with minimum titer of 106 EID50 and maximum titer of 107 EID50/ vaccine dose
Chickens, adult hens
It is intended for the specific prophylaxis of Newcastle disease in receptive species, especially for the first (10-11 days) and second (21-22 days) vaccination due to good immunity and to the fact that the postvaccinal reactions are very mild, but it can be used for all vaccinations, with very good results, including the immunity maintenance vaccinations.
Vaccinate only healthy fowls in good condition. The onset of immunity takes place 10 days after vaccination. Immunity lasts for: 4 months.
Normally, Avipestivac Cl-90 vaccine does not cause postvaccinal reactions. Sometimes, after aerosol vaccination of the flock carrying conditional pathogenic germs, transient, discrete postvaccinal reactions (slight anorexia, dyspnoea, sneeze) may occur in 20 – 30 % of the flock, which subside within 2-3 days. The chickens vaccinated by eye instillation may develop discrete conjunctivitis, in a small proportion, which subsides within 2-3 days.
DOSAGE FOR EACH SPECIES, ROUTE(S) AND METHOD OF ADMINISTRATION
– by oculo-conjunctival or nasal route: apply a dose of the reconstituted vaccine in each eye or nostril (reconstitute each vaccine dose in 0.1 ml diluent; in order to administer the recommended dose, check as to provide 20 drops/ml from the reconstituted vaccine)
– by intramuscular route: reconstitute each vaccine dose in 0.2 ml diluent.
– reconstitute each vaccine dose in 10-40 ml drinking water depending on the age of fowls; 10 ml for chickens up to 30 days old, 20 ml for chickens over 30 days old etc.
– by aerial route (aerosols), reconstitute each vaccine dose in 0.5-2 ml, depending on the device used, with drinking water without disinfectants as diluent;
ADVICE ON CORRECT ADMINISTRATION
The appropriate vaccination period depends on the epizootic condition of the flocks and area where fowls are reared. For farm-reared fowls, vaccination is recommended at the age of 10-11 days with booster after 22-23 days. The subsequent vaccination for immunity maintenance should be carried out after monitoring the immunity status by serological examinations.
For individual administration, use syringes and/or single use needles or moist heat-sterilized.
If administered by aerosols, use aerosol administration devices which form 40-60 microns particles for the first two vaccinations and devices forming 10-20 microns particles for the following vaccinations.
If administered in the drinking water it is very important to provide a 2-4 hours hydrous diet according to the season and then provide the watering system. Add the diluent-reconstituted vaccine in the fresh, clean, disinfectant-free drinking water, after cleaning the drinkers and rinsing them with clear water. Do not provide another drinking water unless the whole vaccine is drunk. To protect the vaccine virus, add 2-3‰ powder milk.
Administer immediately the vaccine after rehydration (maximum 3 hours).
Depending on the epizootic condition of the flocks, Avipestivac Cl-90 can be administered at the same time with other biological products (e.g. Birovac -H120 vaccine against avian bronchitis).
Meat, eggs = 0 days.
Vials with 25, 50, 100, 200, 250, 500, 1000, 1500, 2000 or 2500 doses.
The individual administration vaccine (25-200 doses) is delivered together with the diluent appropriate to the number of doses.