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Solution for injection
For prevention of hypocalcaemia, anaphylactic or allergic conditions
COMPOSITION
Active substances: Calcium chloride 10 g; Magnesium chloride 2.5 g
Excipient (distilled water) ad 100 ml
PHARMACOLOGICAL ACTION
Calcium ion is involved in many physiological processes, as follows: increases the ostheosynthesis, neuromuscular tone, phagocytosis and blood coagulation (by favoring the conversion of prothrombin to thrombin), activity of trypsin and other glycolytic enzymes; reduces edema by decreasing the vascular permeability and activation of diuresis. It acts as antiallergenic and anti-inflammatory agent.
Magnesium ion acts as calcium antagonist: depress the central nervous system, cardiac activity, intestine tonus, blood pressure and produces uterus relaxation, favoring the implantation.
Combination of these chlorides provides a moderate action by reducing the effects of both substances, acting as a tonic for the heart and central nervous system.
TARGET SPECIES
Horses, cattle, sheep, goats, swine, dogs and cats.
INDICATIONS
Tetany, spasmophilia, paresis, ante- and postpartum paraplegia, milk fever, serum sickness, anaphylaxis, hypocalcaemia
The product may be used safely during pregnancy and lactation period.
CONTRAINDICATIONS
Do not use in animals with severe renal failure.
ADVERSE REACTIONS
None known
METHOD OF ADMINISTRATION
The product is injected slowly, strictly intravenously, depending on the species, as follows:
– adult cattle and horses and youth over the age of 12 months: 100 – 400 ml
– adult sheep, goats, swine and young horses and cattle up to the age of 12 months: 20 – 50 ml
– piglets, lambs and kids: 5 – 10 ml
– cats: 0,5 – 2 ml
– dogs: 1 – 10 ml, depending on size.
If necessary, repeat the doses after 24 hours.
WARNINGS
Calciu Magneziu solution is administered strictly intravenously by slow injection
Do not mix Calciu Magneziu solution in the same syringe with other products to be administered.
The intravenous injection is discontinued if tremors of anconeus muscles or of hindquarters occur. The product should not be administered at low temperatures but at body temperature in order to avoid the cardiac syncope.
WITHDRAWAL PERIOD
Meat and offal: zero days
Milk: zero days.
PRESENTATION FORM
Bottles with 20, 50, 100 or 250 ml.
