Solution for injection
Active substance: Ketamine hydrochloride 100 mg/ml
Excipient (water for injection) up to 1 ml
Ketamine is a synthesis product which belongs to non barbiturate anesthetics. Unlike the classical anesthetics, Ketamine induces “dissociative anesthesia “, characterized by superficial sleep with remarkable analgesia, since it blocks the nervous influx at the cortex, without depressing the vital centers. Although a slight decrease of the respiratory frequency is noticed, the product does not significantly influence the respiratory center and the pharyngeal and laryngeal reflexes are maintained.
The product is nontoxic, induces no hypertension and is rapidly eliminated by kidneys avoiding build-up intoxication. The anesthesia is effective immediately if administered by intravenous route and after 8-10 minutes if administered by intramuscular route. The anesthesia lasts 15-30 minutes; if necessary, the anesthesia can be extended as specified in the “method of administration”.
Horses, cattle, sheep, goats, dogs and cats
Ketalrom 100 is intended for all mentioned target species, in case of surgeries, for the examination of stubborn animals, using the appropriate doses and premedication if necessary.
Do not use Ketalrom 100 in hypertensive animals or in glaucoma; decompensate cardiopathy and severe renal failure.
Do not use in case of hypersensitivity to the active substance.
Do not use the product simultaneously with spasmolytics.
After the animals recover from anesthesia, arterial hypertension, tachycardia, salivation, nausea, vomit, respiratory disorders and psychomotor restlessness may occur.
Should you notice severe adverse reactions or any other effects not mentioned in the leaflet, please inform your veterinarian.
Method of administration
The initial inoculation is carried out intramuscularly or intravenously and induces an anesthesia of about 30 minutes. The prolongation of the anesthesia is obtained with a second intramuscular or intravenous injection, using half of the initial dose and with a third injection 30 minutes later, using a quarter of the dose. In the specified species, administer 0.5 mg Diazepam/kg body weight as premedication 15 minutes before anesthesia by intravenous route and 0.15 mg ATROPINĂ SULFURICĂ/kg body weight by subcutaneous route.
Premedication with appropriate doses of Trankilrom – solution for injection may be carried out also previously to anesthesia.
The doses expressed in mg of ketamine per kg of body weight are the following:
- In horses: 1.5-2 ml KETALROM 100/100 kg body weight (1.5-2 mg s.a./kg body weight) by intramuscular or intravenous route
- In ruminants (cattle, sheep, goats): 8-10 ml Ketalrom 100/100 kg body weight (8-10 mg s.a./kg body weight) by intramuscular, subcutaneous or intravenous route
- In dogs and cats:
– Intravenous administration: 0.06 ml Ketalrom 100/kg body weight (6 mg s.a./kg body weight).
– Intramuscular administration:
In dogs: 0.1 ml KETALROM 100 /kg body weight (10 mg s.a./kg body weight);
In cats: 0.15-0.2 ml Ketalrom 100 /kg body weight (15-20 mg s.a./kg body weight).
Until the complete awakening, protect the animals from noise and light.
In case of prolonged anesthesia, water the cornea with physiological solution.
If animals are restless when awake, administer 0.5 mg Diazepam /kg body weight by intravenous route.
Reduce the dose in animals with renal deficiency.
Simultaneous administration of ketamine hydrochloride and spasmolytics by intravenous route may cause animal death. The intravenous injection should be carried out very slowly. Assess accurately the animal weight to avoid overdose and underdose. An overdose can cause cardiac arrest. An overdose or fast administration of ketamine hydrochloride can cause respiratory depression, in which case mechanic ventilation should be initiated.
To be supplied only on veterinary prescription.
Meat and organs: 0 days
Milk: 0 days
The vials contain 20 ml product and are individually packed into cardboard boxes.